Identification of Synergistic, Clinically Achievable, Combination Therapies for Osteosarcoma

Systemic therapy has improved osteosarcoma event-free and overall survival, but 30–50% of patients originally diagnosed will have progressive or recurrent disease, which is difficult to cure. Osteosarcoma has a complex karyotype, with loss of p53 in the vast majority of cases and an absence of recur...

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Detalles Bibliográficos
Autores principales: Yu, Diana, Kahen, Elliot, Cubitt, Christopher L., McGuire, Jeremy, Kreahling, Jenny, Lee, Jae, Altiok, Soner, Lynch, Conor C., Sullivan, Daniel M., Reed, Damon R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658502/
https://www.ncbi.nlm.nih.gov/pubmed/26601688
http://dx.doi.org/10.1038/srep16991

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658502/
https://www.ncbi.nlm.nih.gov/pubmed/26601688
http://dx.doi.org/10.1038/srep16991

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