Shearing of the CENP-A dimerization interface mediates plasticity in the octameric centromeric nucleosome

The centromeric nucleosome is a key epigenetic determinant of centromere identity and function. Consequently, deciphering how CENP-A containing nucleosomes contribute structurally to centromere function is a fundamental question in chromosome biology. Here, we performed microsecond timescale all-ato...

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Detalles Bibliográficos
Autores principales: Winogradoff, David, Zhao, Haiqing, Dalal, Yamini, Papoian, Garegin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658507/
https://www.ncbi.nlm.nih.gov/pubmed/26602160
http://dx.doi.org/10.1038/srep17038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658507/
https://www.ncbi.nlm.nih.gov/pubmed/26602160
http://dx.doi.org/10.1038/srep17038

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