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Shearing of the CENP-A dimerization interface mediates plasticity in the octameric centromeric nucleosome

The centromeric nucleosome is a key epigenetic determinant of centromere identity and function. Consequently, deciphering how CENP-A containing nucleosomes contribute structurally to centromere function is a fundamental question in chromosome biology. Here, we performed microsecond timescale all-ato...

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Detalles Bibliográficos
Autores principales:	Winogradoff, David, Zhao, Haiqing, Dalal, Yamini, Papoian, Garegin A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658507/ https://www.ncbi.nlm.nih.gov/pubmed/26602160 http://dx.doi.org/10.1038/srep17038

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