Impact of Mycobacterium tuberculosis RD1-locus on human primary dendritic cell immune functions

Modern strategies to develop vaccines against Mycobacterium tuberculosis (Mtb) aim to improve the current Bacillus Calmette-Guerin (BCG) vaccine or to attenuate the virulence of Mtb vaccine candidates. In the present study, the impact of wild type or mutated region of difference 1 (RD1) variants on...

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Detalles Bibliográficos
Autores principales: Etna, Marilena P., Giacomini, Elena, Pardini, Manuela, Severa, Martina, Bottai, Daria, Cruciani, Melania, Rizzo, Fabiana, Calogero, Raffaele, Brosch, Roland, Coccia, Eliana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658526/
https://www.ncbi.nlm.nih.gov/pubmed/26602835
http://dx.doi.org/10.1038/srep17078