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In vitro activity of phospholipase A(2) and of peptides from Crotalus durissus terrificus venom against amastigote and promastigote forms of Leishmania (L.) infantum chagasi

BACKGROUND: American visceral leishmaniasis is caused by the intracellular parasite Leishmania (L.) infantum chagasi, and transmitted by the sand fly Lutzomyia longipalpis. Since treatment is based on classical chemotherapeutics with significant side effects, the search for new drugs remains the gre...

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Detalles Bibliográficos
Autores principales: Barros, Gustavo A. C., Pereira, Andreia V., Barros, Luciana C., Jr, Airton Lourenço, Calvi, Sueli A., Santos, Lucilene D., Barraviera, Benedito, Ferreira, Rui Seabra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658749/
https://www.ncbi.nlm.nih.gov/pubmed/26609302
http://dx.doi.org/10.1186/s40409-015-0049-0