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Analysis of nucleosome positioning landscapes enables gene discovery in the human malaria parasite Plasmodium falciparum

BACKGROUND: Plasmodium falciparum, the deadliest malaria-causing parasite, has an extremely AT-rich (80.7 %) genome. Because of high AT-content, sequence-based annotation of genes and functional elements remains challenging. In order to better understand the regulatory network controlling gene expre...

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Detalles Bibliográficos
Autores principales: Lu, Xueqing Maggie, Bunnik, Evelien M., Pokhriyal, Neeti, Nasseri, Sara, Lonardi, Stefano, Le Roch, Karine G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658763/
https://www.ncbi.nlm.nih.gov/pubmed/26607328
http://dx.doi.org/10.1186/s12864-015-2214-9