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Lithium protects dopaminergic cells from rotenone toxicity via autophagy enhancement

BACKGROUND: Previous studies have indicated that enhancement of autophagy lysosome pathway may be beneficial for Parkinson’s disease (PD), in which aberrant accumulation of aggregated/misfolded proteins and mitochondrial dysfunction are considered as crucial pathogenesis. Recently, a number of studi...

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Detalles Bibliográficos
Autores principales: Hou, Lingling, Xiong, Nian, Liu, Ling, Huang, Jinsha, Han, Chao, Zhang, Guoxin, Li, Jie, Xu, Xiaoyun, Lin, Zhicheng, Wang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658766/
https://www.ncbi.nlm.nih.gov/pubmed/26608648
http://dx.doi.org/10.1186/s12868-015-0222-y