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Soluble PD-1 aggravates progression of collagen-induced arthritis through Th1 and Th17 pathways
INTRODUCTION: The programmed cell death 1 (PD-1) protein is a critical regulator of T-cell activation and is also an important therapeutic target for autoimmune diseases. Little is known about the regulation and functional properties of the soluble PD-1 (sPD-1) variant. The aim of this study was to...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659197/ https://www.ncbi.nlm.nih.gov/pubmed/26608464 http://dx.doi.org/10.1186/s13075-015-0859-z |