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Soluble PD-1 aggravates progression of collagen-induced arthritis through Th1 and Th17 pathways

INTRODUCTION: The programmed cell death 1 (PD-1) protein is a critical regulator of T-cell activation and is also an important therapeutic target for autoimmune diseases. Little is known about the regulation and functional properties of the soluble PD-1 (sPD-1) variant. The aim of this study was to...

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Detalles Bibliográficos
Autores principales:	Liu, Cuiping, Jiang, Juean, Gao, Li, Wang, Xiaoting, Hu, Xiaohan, Wu, Min, Wu, Jian, Xu, Ting, Shi, Qin, Zhang, Xueguang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659197/ https://www.ncbi.nlm.nih.gov/pubmed/26608464 http://dx.doi.org/10.1186/s13075-015-0859-z

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