Preferential sites for intramolecular glucosepane cross-link formation in type I collagen: A thermodynamic study

The extracellular matrix (ECM) undergoes progressive age-related stiffening and loss of proteolytic digestibility due to an increase in concentration of advanced glycation end products (AGEs). The most abundant AGE, glucosepane, accumulates in collagen with concentrations over 100 times greater than...

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Detalles Bibliográficos
Autores principales: Collier, Thomas A., Nash, Anthony, Birch, Helen L., de Leeuw, Nora H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659457/
https://www.ncbi.nlm.nih.gov/pubmed/26049074
http://dx.doi.org/10.1016/j.matbio.2015.06.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659457/
https://www.ncbi.nlm.nih.gov/pubmed/26049074
http://dx.doi.org/10.1016/j.matbio.2015.06.001

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