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RNA Futile Cycling in Model Persisters Derived from MazF Accumulation

Metabolism plays an important role in the persister phenotype, as evidenced by the number of strategies that perturb metabolism to sabotage this troublesome subpopulation. However, the absence of techniques to isolate high-purity populations of native persisters has precluded direct measurement of p...

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Detalles Bibliográficos
Autores principales: Mok, Wendy W. K., Park, Junyoung O., Rabinowitz, Joshua D., Brynildsen, Mark P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659464/
https://www.ncbi.nlm.nih.gov/pubmed/26578677
http://dx.doi.org/10.1128/mBio.01588-15