DNA-Containing Immunocomplexes Promote Inflammasome Assembly and Release of Pyrogenic Cytokines by CD14(+) CD16(+) CD64(high) CD32(low) Inflammatory Monocytes from Malaria Patients

High levels of circulating immunocomplexes (ICs) are found in patients with either infectious or sterile inflammation. We report that patients with either Plasmodium falciparum or Plasmodium vivax malaria have increased levels of circulating anti-DNA antibodies and ICs containing parasite DNA. Upon...

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Detalles Bibliográficos
Autores principales: Hirako, Isabella C., Gallego-Marin, Carolina, Ataide, Marco A., Andrade, Warrison A., Gravina, Humberto, Rocha, Bruno C., de Oliveira, Rosane B., Pereira, Dhelio B., Vinetz, Joseph, Diamond, Betty, Ram, Sanjay, Golenbock, Douglas T., Gazzinelli, Ricardo T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659466/
https://www.ncbi.nlm.nih.gov/pubmed/26578679
http://dx.doi.org/10.1128/mBio.01605-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659466/
https://www.ncbi.nlm.nih.gov/pubmed/26578679
http://dx.doi.org/10.1128/mBio.01605-15

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