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Novel Alleles of gon-2, a C. elegans Ortholog of Mammalian TRPM6 and TRPM7, Obtained by Genetic Reversion Screens

TRP (Transient Receptor Potential) cation channels of the TRPM subfamily have been found to be critically important for the regulation of Mg(2+) homeostasis in both protostomes (e.g., the nematode, C. elegans, and the insect, D. melanogaster) and deuterostomes (e.g., humans). Although significant pr...

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Detalles Bibliográficos
Autores principales: Lambie, Eric J., Bruce, Robert D., Zielich, Jeffrey, Yuen, Sonia N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659536/
https://www.ncbi.nlm.nih.gov/pubmed/26606136
http://dx.doi.org/10.1371/journal.pone.0143445