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Mechanism of Action of Two Flavone Isomers Targeting Cancer Cells with Varying Cell Differentiation Status

Apoptosis can be triggered in two different ways, through the intrinsic or the extrinsic pathway. The intrinsic pathway is mediated by the mitochondria via the release of cytochrome C while the extrinsic pathway is prompted by death receptor signals and bypasses the mitochondria. These two pathways...

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Detalles Bibliográficos
Autores principales: LeJeune, Timothy M., Tsui, Hei Yin, Parsons, Laura B., Miller, Gerald E., Whitted, Crystal, Lynch, Kayla E., Ramsauer, Robert E., Patel, Jasmine U., Wyatt, Jarrett E., Street, Doris S., Adams, Carolyn B., McPherson, Brian, Tsui, Hei Man, Evans, Julie A., Livesay, Christopher, Torrenegra, Ruben D., Palau, Victoria E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659548/
https://www.ncbi.nlm.nih.gov/pubmed/26606169
http://dx.doi.org/10.1371/journal.pone.0142928