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Mechanism of Action of Two Flavone Isomers Targeting Cancer Cells with Varying Cell Differentiation Status
Apoptosis can be triggered in two different ways, through the intrinsic or the extrinsic pathway. The intrinsic pathway is mediated by the mitochondria via the release of cytochrome C while the extrinsic pathway is prompted by death receptor signals and bypasses the mitochondria. These two pathways...
Autores principales: | LeJeune, Timothy M., Tsui, Hei Yin, Parsons, Laura B., Miller, Gerald E., Whitted, Crystal, Lynch, Kayla E., Ramsauer, Robert E., Patel, Jasmine U., Wyatt, Jarrett E., Street, Doris S., Adams, Carolyn B., McPherson, Brian, Tsui, Hei Man, Evans, Julie A., Livesay, Christopher, Torrenegra, Ruben D., Palau, Victoria E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659548/ https://www.ncbi.nlm.nih.gov/pubmed/26606169 http://dx.doi.org/10.1371/journal.pone.0142928 |
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