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Automated Classification and Cluster Visualization of Genotypes Derived from High Resolution Melt Curves

INTRODUCTION: High Resolution Melting (HRM) following PCR has been used to identify DNA genotypes. Fluorescent dyes bounded to double strand DNA lose their fluorescence with increasing temperature, yielding different signatures for different genotypes. Recent software tools have been made available...

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Detalles Bibliográficos
Autores principales: Kanderian, Sami, Jiang, Lingxia, Knight, Ivor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659556/
https://www.ncbi.nlm.nih.gov/pubmed/26605797
http://dx.doi.org/10.1371/journal.pone.0143295