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Automated Classification and Cluster Visualization of Genotypes Derived from High Resolution Melt Curves
INTRODUCTION: High Resolution Melting (HRM) following PCR has been used to identify DNA genotypes. Fluorescent dyes bounded to double strand DNA lose their fluorescence with increasing temperature, yielding different signatures for different genotypes. Recent software tools have been made available...
Autores principales: | Kanderian, Sami, Jiang, Lingxia, Knight, Ivor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659556/ https://www.ncbi.nlm.nih.gov/pubmed/26605797 http://dx.doi.org/10.1371/journal.pone.0143295 |
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