Hepatic Interferon-λ3 (IFNL3) Gene Expression Reveals Not to Be Attenuated in Non-Favorable IFNL3 rs4803217 or IFNL4 rs368234815 Minor Allele Carriers in Chronic Hepatitis C

Genetic polymorphisms in the region of the interferon-λ genes (IFNL) associate with clearance of hepatitis C virus (HCV) infection. One of these polymorphisms, IFNL4 rs368234815, determines loss or gain of function of the IFNL4 gene by frameshift variation. The very same and a second one, IFNL3 rs48...

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Detalles Bibliográficos
Autores principales: Amanzada, Ahmad, Reinhardt, Lars, Fey, Dorothea, Zeisberg, Elisabeth M., Mihm, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659612/
https://www.ncbi.nlm.nih.gov/pubmed/26606750
http://dx.doi.org/10.1371/journal.pone.0143783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659612/
https://www.ncbi.nlm.nih.gov/pubmed/26606750
http://dx.doi.org/10.1371/journal.pone.0143783

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