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Characterization of Leukemia-Inducing Genes Using a Proto-Oncogene/Homeobox Gene Retroviral Human cDNA Library in a Mouse In Vivo Model

The purpose of this research is to develop a method to screen a large number of potential driver mutations of acute myeloid leukemia (AML) using a retroviral cDNA library and murine bone marrow transduction-transplantation system. As a proof-of-concept, murine bone marrow (BM) cells were transduced...

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Detalles Bibliográficos
Autores principales: Jang, Su Hwa, Lee, Sohyun, Chung, Hee Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659616/
https://www.ncbi.nlm.nih.gov/pubmed/26606454
http://dx.doi.org/10.1371/journal.pone.0143240