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A new Otogelin ENU mouse model for autosomal-recessive nonsyndromic moderate hearing impairment

Approximately 10 % of the population worldwide suffers from hearing loss (HL) and about 60 % of persons with early onset HL have hereditary hearing loss due to genetic mutations. Highly efficient mutagenesis in mice with the chemical mutagen, ethylnitrosourea (ENU), associated with relevant phenotyp...

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Detalles Bibliográficos
Autores principales: El Hakam Kamareddin, Carole, Magnol, Laetitia, Blanquet, Veronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659790/
https://www.ncbi.nlm.nih.gov/pubmed/26636018
http://dx.doi.org/10.1186/s40064-015-1537-y