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KCNK5 channels mostly expressed in cochlear outer sulcus cells are indispensable for hearing
In the cochlea, K(+) is essential for mechano-electrical transduction. Here, we explore cochlear structure and function in mice lacking K(+) channels of the two-pore domain family. A profound deafness associated with a decrease in endocochlear potential is found in adult Kcnk5(−/−) mice. Hearing occ...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659937/ https://www.ncbi.nlm.nih.gov/pubmed/26549439 http://dx.doi.org/10.1038/ncomms9780 |