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The impact of next-generation sequencing technologies on HLA research

In the past decade, the development of next-generation sequencing (NGS) has paved the way for whole-genome analysis in individuals. Research on the human leukocyte antigen (HLA), an extensively studied molecule involved in immunity, has benefitted from NGS technologies. The HLA region, a 3.6-Mb segm...

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Detalles Bibliográficos
Autores principales: Hosomichi, Kazuyoshi, Shiina, Takashi, Tajima, Atsushi, Inoue, Ituro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660052/
https://www.ncbi.nlm.nih.gov/pubmed/26311539
http://dx.doi.org/10.1038/jhg.2015.102