Structure and dynamics of polymyxin-resistance-associated response regulator PmrA in complex with promoter DNA

PmrA, an OmpR/PhoB family response regulator, manages genes for antibiotic resistance. Phosphorylation of OmpR/PhoB response regulator induces the formation of a symmetric dimer in the N-terminal receiver domain (REC), promoting two C-terminal DNA-binding domains (DBDs) to recognize promoter DNA to...

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Detalles Bibliográficos
Autores principales: Lou, Yuan-Chao, Weng, Tsai-Hsuan, Li, Yi-Chuan, Kao, Yi-Fen, Lin, Wei-Feng, Peng, Hwei-Ling, Chou, Shan-Ho, Hsiao, Chwan-Deng, Chen, Chinpan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660055/
https://www.ncbi.nlm.nih.gov/pubmed/26564787
http://dx.doi.org/10.1038/ncomms9838

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660055/
https://www.ncbi.nlm.nih.gov/pubmed/26564787
http://dx.doi.org/10.1038/ncomms9838

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