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Structure and dynamics of polymyxin-resistance-associated response regulator PmrA in complex with promoter DNA
PmrA, an OmpR/PhoB family response regulator, manages genes for antibiotic resistance. Phosphorylation of OmpR/PhoB response regulator induces the formation of a symmetric dimer in the N-terminal receiver domain (REC), promoting two C-terminal DNA-binding domains (DBDs) to recognize promoter DNA to...
Autores principales: | Lou, Yuan-Chao, Weng, Tsai-Hsuan, Li, Yi-Chuan, Kao, Yi-Fen, Lin, Wei-Feng, Peng, Hwei-Ling, Chou, Shan-Ho, Hsiao, Chwan-Deng, Chen, Chinpan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660055/ https://www.ncbi.nlm.nih.gov/pubmed/26564787 http://dx.doi.org/10.1038/ncomms9838 |
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