Formin and capping protein together embrace the actin filament in a ménage à trois

Proteins targeting actin filament barbed ends play a pivotal role in motile processes. While formins enhance filament assembly, capping protein (CP) blocks polymerization. On their own, they both bind barbed ends with high affinity and very slow dissociation. Their barbed-end binding is thought to b...

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Detalles Bibliográficos
Autores principales: Shekhar, Shashank, Kerleau, Mikael, Kühn, Sonja, Pernier, Julien, Romet-Lemonne, Guillaume, Jégou, Antoine, Carlier, Marie-France
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660058/
https://www.ncbi.nlm.nih.gov/pubmed/26564775
http://dx.doi.org/10.1038/ncomms9730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660058/
https://www.ncbi.nlm.nih.gov/pubmed/26564775
http://dx.doi.org/10.1038/ncomms9730

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