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The molecular architecture of the Dam1 kinetochore complex is defined by cross-linking based structural modelling
Accurate segregation of chromosomes during cell division is essential. The Dam1 complex binds kinetochores to microtubules and its oligomerization is required to form strong attachments. It is a key target of Aurora B kinase, which destabilizes erroneous attachments allowing subsequent correction. U...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660060/ https://www.ncbi.nlm.nih.gov/pubmed/26560693 http://dx.doi.org/10.1038/ncomms9673 |