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The molecular architecture of the Dam1 kinetochore complex is defined by cross-linking based structural modelling

Accurate segregation of chromosomes during cell division is essential. The Dam1 complex binds kinetochores to microtubules and its oligomerization is required to form strong attachments. It is a key target of Aurora B kinase, which destabilizes erroneous attachments allowing subsequent correction. U...

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Detalles Bibliográficos
Autores principales: Zelter, Alex, Bonomi, Massimiliano, Kim, Jae ook, Umbreit, Neil T., Hoopmann, Michael R., Johnson, Richard, Riffle, Michael, Jaschob, Daniel, MacCoss, Michael J., Moritz, Robert L., Davis, Trisha N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660060/
https://www.ncbi.nlm.nih.gov/pubmed/26560693
http://dx.doi.org/10.1038/ncomms9673