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Understanding the link between single cell and population scale responses of Escherichia coli in differing ligand gradients

We formulate an agent-based population model of Escherichia coli cells which incorporates a description of the chemotaxis signalling cascade at the single cell scale. The model is used to gain insight into the link between the signalling cascade dynamics and the overall population response to differ...

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Detalles Bibliográficos
Autores principales: Edgington, Matthew P., Tindall, Marcus J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660157/
https://www.ncbi.nlm.nih.gov/pubmed/26693274
http://dx.doi.org/10.1016/j.csbj.2015.09.003