Identifying and quantifying two ligand-binding sites while imaging native human membrane receptors by AFM

A current challenge in life sciences is to image cell membrane receptors while characterizing their specific interactions with various ligands. Addressing this issue has been hampered by the lack of suitable nanoscopic methods. Here we address this challenge and introduce multifunctional high-resolu...

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Detalles Bibliográficos
Autores principales: Pfreundschuh, Moritz, Alsteens, David, Wieneke, Ralph, Zhang, Cheng, Coughlin, Shaun R., Tampé, Robert, Kobilka, Brian K., Müller, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660198/
https://www.ncbi.nlm.nih.gov/pubmed/26561004
http://dx.doi.org/10.1038/ncomms9857

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660198/
https://www.ncbi.nlm.nih.gov/pubmed/26561004
http://dx.doi.org/10.1038/ncomms9857

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