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Aneuploidy causes premature differentiation of neural and intestinal stem cells

Aneuploidy is associated with a variety of diseases such as cancer and microcephaly. Although many studies have addressed the consequences of a non-euploid genome in cells, little is known about their overall consequences in tissue and organism development. Here we use two different mutant condition...

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Detalles Bibliográficos
Autores principales: Gogendeau, Delphine, Siudeja, Katarzyna, Gambarotto, Davide, Pennetier, Carole, Bardin, Allison J., Basto, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660207/
https://www.ncbi.nlm.nih.gov/pubmed/26573328
http://dx.doi.org/10.1038/ncomms9894