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Comprehensive functional characterization of cancer–testis antigens defines obligate participation in multiple hallmarks of cancer

Tumours frequently activate genes whose expression is otherwise biased to the testis, collectively known as cancer–testis antigens (CTAs). The extent to which CTA expression represents epiphenomena or confers tumorigenic traits is unknown. In this study, to address this, we implemented a multidimens...

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Detalles Bibliográficos
Autores principales: Maxfield, Kimberly E., Taus, Patrick J., Corcoran, Kathleen, Wooten, Joshua, Macion, Jennifer, Zhou, Yunyun, Borromeo, Mark, Kollipara, Rahul K., Yan, Jingsheng, Xie, Yang, Xie, Xian-Jin, Whitehurst, Angelique W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660212/
https://www.ncbi.nlm.nih.gov/pubmed/26567849
http://dx.doi.org/10.1038/ncomms9840