Spindle assembly checkpoint inactivation fails to suppress neuroblast tumour formation in aurA mutant Drosophila

Tissue homeostasis requires accurate control of cell proliferation, differentiation and chromosome segregation. Drosophila sas-4 and aurA mutants present brain tumours with extra neuroblasts (NBs), defective mitotic spindle assembly and delayed mitosis due to activation of the spindle assembly check...

Descripción completa

Detalles Bibliográficos
Autores principales: Caous, Renaud, Pascal, Aude, Romé, Pierre, Richard-Parpaillon, Laurent, Karess, Roger, Giet, Régis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660220/
https://www.ncbi.nlm.nih.gov/pubmed/26568519
http://dx.doi.org/10.1038/ncomms9879

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660220/
https://www.ncbi.nlm.nih.gov/pubmed/26568519
http://dx.doi.org/10.1038/ncomms9879

Ejemplares similares