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Spindle assembly checkpoint inactivation fails to suppress neuroblast tumour formation in aurA mutant Drosophila

Tissue homeostasis requires accurate control of cell proliferation, differentiation and chromosome segregation. Drosophila sas-4 and aurA mutants present brain tumours with extra neuroblasts (NBs), defective mitotic spindle assembly and delayed mitosis due to activation of the spindle assembly check...

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Detalles Bibliográficos
Autores principales:	Caous, Renaud, Pascal, Aude, Romé, Pierre, Richard-Parpaillon, Laurent, Karess, Roger, Giet, Régis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Pub. Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660220/ https://www.ncbi.nlm.nih.gov/pubmed/26568519 http://dx.doi.org/10.1038/ncomms9879

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