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Parvalbumin-positive interneurons of the prefrontal cortex support working memory and cognitive flexibility

Dysfunction of parvalbumin (PV)-positive GABAergic interneurons (PVIs) within the prefrontal cortex (PFC) has been implicated in schizophrenia pathology. It is however unclear, how impaired signaling of these neurons may contribute to PFC dysfunction. To identify how PVIs contribute to PFC-dependent...

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Detalles Bibliográficos
Autores principales: Murray, Andrew J., Woloszynowska-Fraser, Marta U., Ansel-Bollepalli, Laura, Cole, Katy L. H., Foggetti, Angelica, Crouch, Barry, Riedel, Gernot, Wulff, Peer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660359/
https://www.ncbi.nlm.nih.gov/pubmed/26608841
http://dx.doi.org/10.1038/srep16778