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Genetic polymorphisms of PCSK2 are associated with glucose homeostasis and progression to type 2 diabetes in a Chinese population

Proprotein convertase subtilisin/kexin type 2 (PCSK2) is a prohormone processing enzyme involved in insulin and glucagon biosynthesis. We previously found the genetic polymorphism of PCSK2 on chromosome 20 was responsible for the linkage peak of several glucose homeostasis parameters. The aim of thi...

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Detalles Bibliográficos
Autores principales: Chang, Tien-Jyun, Chiu, Yen-Feng, Sheu, Wayne H-H., Shih, Kuang-Chung, Hwu, Chii-Min, Quertermous, Thomas, Jou, Yuh-Shan, Kuo, Shan-Shan, Chang, Yi-Cheng, Chuang, Lee-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660384/
https://www.ncbi.nlm.nih.gov/pubmed/26607656
http://dx.doi.org/10.1038/srep14380