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Defining an additivity framework for mixture research in inducible whole-cell biosensors

A novel additivity framework for mixture effect modelling in the context of whole cell inducible biosensors has been mathematically developed and implemented in R. The proposed method is a multivariate extension of the effective dose (ED(p)) concept. Specifically, the extension accounts for differen...

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Detalles Bibliográficos
Autores principales: Martin-Betancor, K., Ritz, C., Fernández-Piñas, F., Leganés, F., Rodea-Palomares, I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660423/
https://www.ncbi.nlm.nih.gov/pubmed/26606975
http://dx.doi.org/10.1038/srep17200