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Intra- and inter-nucleosomal interactions of the histone H4 tail revealed with a human nucleosome core particle with genetically-incorporated H4 tetra-acetylation

Post-translational modifications (PTMs) of histones, such as lysine acetylation of the N-terminal tails, play crucial roles in controlling gene expression. Due to the difficulty in reconstituting site-specifically acetylated nucleosomes with crystallization quality, structural analyses of histone ac...

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Detalles Bibliográficos
Autores principales: Wakamori, Masatoshi, Fujii, Yoshifumi, Suka, Noriyuki, Shirouzu, Mikako, Sakamoto, Kensaku, Umehara, Takashi, Yokoyama, Shigeyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660432/
https://www.ncbi.nlm.nih.gov/pubmed/26607036
http://dx.doi.org/10.1038/srep17204