Fluoride-containing podophyllum derivatives exhibit antitumor activities through enhancing mitochondrial apoptosis pathway by increasing the expression of caspase-9 in HeLa cells

This work aims to provide sampling of halogen-containing aniline podophyllum derivatives and their mode of action with an in-depth comparison among fluorine, chloride and bromide for clarifying the important role and impact of fluorine substitution on enhancing antitumor activity, with an emphasis o...

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Detalles Bibliográficos
Autores principales: Zhao, Wei, Yang, Yong, Zhang, Ya-Xuan, Zhou, Chen, Li, Hong-Mei, Tang, Ya-Ling, Liang, Xin-Hua, Chen, Tao, Tang, Ya-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660440/
https://www.ncbi.nlm.nih.gov/pubmed/26608216
http://dx.doi.org/10.1038/srep17175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660440/
https://www.ncbi.nlm.nih.gov/pubmed/26608216
http://dx.doi.org/10.1038/srep17175

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