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Oleanolic Acid Prevents Increase in Blood Pressure and Nephrotoxicity in Nitric Oxide Dependent Type of Hypertension in Rats

BACKGROUND: Recently, we have reported antihypertensive activity of oleanolic acid (OA) in glucocorticoid-induced hypertension with restoration of nitric oxide (NO) level. However, the involvement of NO-releasing action of OA was unclear. OBJECTIVE: To explore antihypertensive activity of OA in N(ω)...

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Detalles Bibliográficos
Autores principales: Bachhav, Sagar S., Bhutada, Mukesh S., Patil, Sachin P., Sharma, Kinjal S., Patil, Savita D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660519/
https://www.ncbi.nlm.nih.gov/pubmed/26692754
http://dx.doi.org/10.4103/0974-8490.159575