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Mode of interaction of the Gαo subunit of heterotrimeric G proteins with the GoLoco1 motif of Drosophila Pins is determined by guanine nucleotides

Drosophila GoLoco motif-containing protein Pins is unusual in its highly efficient interaction with both GDP- and the GTP-loaded forms of the α-subunit of the heterotrimeric Go protein. We analysed the interactions of Gαo in its two nucleotide forms with GoLoco1–the first of the three GoLoco domains...

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Detalles Bibliográficos
Autores principales: Lüchtenborg, Anne-Marie, Purvanov, Vladimir, Melnik, Bogdan S., Becker, Simon, Katanaev, Vladimir L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660580/
https://www.ncbi.nlm.nih.gov/pubmed/26487707
http://dx.doi.org/10.1042/BSR20150201