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Mode of interaction of the Gαo subunit of heterotrimeric G proteins with the GoLoco1 motif of Drosophila Pins is determined by guanine nucleotides
Drosophila GoLoco motif-containing protein Pins is unusual in its highly efficient interaction with both GDP- and the GTP-loaded forms of the α-subunit of the heterotrimeric Go protein. We analysed the interactions of Gαo in its two nucleotide forms with GoLoco1–the first of the three GoLoco domains...
Autores principales: | Lüchtenborg, Anne-Marie, Purvanov, Vladimir, Melnik, Bogdan S., Becker, Simon, Katanaev, Vladimir L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660580/ https://www.ncbi.nlm.nih.gov/pubmed/26487707 http://dx.doi.org/10.1042/BSR20150201 |
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