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The expression and activity of thioredoxin reductase 1 splice variants v1 and v2 regulate the expression of genes associated with differentiation and adhesion

The mammalian redox-active selenoprotein thioredoxin reductase (TrxR1) is a main player in redox homoeostasis. It transfers electrons from NADPH to a large variety of substrates, particularly to those containing redox-active cysteines. Previously, we reported that the classical form of cytosolic Trx...

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Detalles Bibliográficos
Autores principales: Nalvarte, Ivan, Damdimopoulos, Anastasios E., Rüegg, Joëlle, Spyrou, Giannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660583/
https://www.ncbi.nlm.nih.gov/pubmed/26464515
http://dx.doi.org/10.1042/BSR20150236