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Scutellarin regulates microglia-mediated TNC1 astrocytic reaction and astrogliosis in cerebral ischemia in the adult rats

BACKGROUND: Scutellarin, an anti-inflammatory agent, effectively suppressed microglia activation in rats with middle cerebral artery occlusion (MCAO). Robust microglia activation, acute in onset, was followed by astrogliosis. This study was aimed to determine if scutellarin would also affect the rea...

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Detalles Bibliográficos
Autores principales: Fang, Ming, Yuan, Yun, Rangarajan, Parakalan, Lu, Jia, Wu, Yajun, Wang, Huadong, Wu, Chunyun, Ling, Eng-Ang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660684/
https://www.ncbi.nlm.nih.gov/pubmed/26608466
http://dx.doi.org/10.1186/s12868-015-0219-6