Downregulation of the small GTPase SAR1A: a key event underlying alcohol-induced Golgi fragmentation in hepatocytes

The hepatic asialoglycoprotein receptor (ASGP-R) is posttranslationally modified in the Golgi en route to the plasma membrane, where it mediates clearance of desialylated serum glycoproteins. It is known that content of plasma membrane-associated ASGP-R is decreased after ethanol exposure, although...

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Detalles Bibliográficos
Autores principales: Petrosyan, Armen, Cheng, Pi-Wan, Clemens, Dahn L., Casey, Carol A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660820/
https://www.ncbi.nlm.nih.gov/pubmed/26607390
http://dx.doi.org/10.1038/srep17127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660820/
https://www.ncbi.nlm.nih.gov/pubmed/26607390
http://dx.doi.org/10.1038/srep17127

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