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The facile construction of the phthalazin-1(2H)-one scaffold via copper-mediated C–H(sp(2))/C–H(sp) coupling under mild conditions
A novel strategy for the construction of the phthalazin-1(2H)-one scaffold has been developed by means of a copper-mediated cascade C–H/C–H coupling and intramolecular annulations and a subsequent facile hydrazinolysis. This C–H activation transformation proceeds smoothly with wide generality, good...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660935/ https://www.ncbi.nlm.nih.gov/pubmed/26664581 http://dx.doi.org/10.3762/bjoc.11.177 |