Two strategies for the synthesis of the biologically important ATP analogue ApppI, at a multi-milligram scale

Two strategies for the synthesis of the ATP (adenosine triphosphate) analogue ApppI [1-adenosin-5’-yl 3-(3-methylbut-3-enyl)triphosphoric acid diester] (1) are described. ApppI is an active metabolite of the mevalonate pathway and thus is of major biological significance. Chemically synthezised Appp...

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Detalles Bibliográficos
Autores principales: Weisell, Janne, Vepsäläinen, Jouko, Turhanen, Petri A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2015
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660979/
https://www.ncbi.nlm.nih.gov/pubmed/26664641
http://dx.doi.org/10.3762/bjoc.11.237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660979/
https://www.ncbi.nlm.nih.gov/pubmed/26664641
http://dx.doi.org/10.3762/bjoc.11.237

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