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Helix-Capping Histidines: Diversity of N–H···N Hydrogen Bond Strength Revealed by (2h)J(NN) Scalar Couplings
[Image: see text] In addition to its well-known roles as an electrophile and general acid, the side chain of histidine often serves as a hydrogen bond (H-bond) acceptor. These H-bonds provide a convenient pH-dependent switch for local structure and functional motifs. In hundreds of instances, a hist...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660981/ https://www.ncbi.nlm.nih.gov/pubmed/26523621 http://dx.doi.org/10.1021/acs.biochem.5b01002 |