Copper-mediated synthesis of N-alkenyl-α,β-unsaturated nitrones and their conversion to tri- and tetrasubstituted pyridines

A Chan–Lam reaction has been used to prepare N-alkenyl-α,β-unsaturated nitrones, which undergo a subsequent thermal rearrangement to the corresponding tri- and tetrasubstituted pyridines. The optimization and scope of these transformations is discussed. Initial mechanistic experiments suggest a reac...

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Detalles Bibliográficos
Autores principales: Kontokosta, Dimitra, Mueller, Daniel S, Mo, Dong-Liang, Pace, Wiktoria H, Simpson, Rachel A, Anderson, Laura L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2015
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660996/
https://www.ncbi.nlm.nih.gov/pubmed/26664630
http://dx.doi.org/10.3762/bjoc.11.226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660996/
https://www.ncbi.nlm.nih.gov/pubmed/26664630
http://dx.doi.org/10.3762/bjoc.11.226

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