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Role for neonatal D-serine signaling: prevention of physiological and behavioral deficits in adult Pick1 knockout mice

NMDA glutamate receptors play key roles in brain development, function, and dysfunction. Regulatory roles of D-serine in NMDA receptor-mediated synaptic plasticity have been reported. Nonetheless, it is unclear whether and how neonatal deficits in NMDA-receptor-mediated neurotransmission affect adul...

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Detalles Bibliográficos
Autores principales: Nomura, Jun, Jaaro-Peled, Hanna, Lewis, Eastman, Nuñez-Abades, Pedro, Huppe-Gourgues, Frederic, Cash-Padgett, Tyler, Emiliani, Francesco, Kondo, Mari A., Furuya, Asako, Landek-Salgado, Melissa A., Ayhan, Yavuz, Kamiya, Atsushi, Takumi, Toru, Huganir, Richard, Pletnikov, Mikhail, O’Donnell, Patricio, Sawa, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661134/
https://www.ncbi.nlm.nih.gov/pubmed/26008737
http://dx.doi.org/10.1038/mp.2015.61