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Insights into brain metastasis in patients with ALK+ lung cancer: is the brain truly a sanctuary?

Anaplastic lymphoma kinase (ALK) has been identified to exert a potent transforming activity through its rearrangement in non-small cell lung cancer (NSCLC), and patients (pts) with ALK rearrangement can be treated more successfully with ALK inhibitors, such as crizotinib, alectinib, and ceritinib,...

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Detalles Bibliográficos
Autores principales: Toyokawa, Gouji, Seto, Takashi, Takenoyama, Mitsuhiro, Ichinose, Yukito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661196/
https://www.ncbi.nlm.nih.gov/pubmed/26342831
http://dx.doi.org/10.1007/s10555-015-9592-y