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High-uptake areas on positron emission tomography with the hypoxic radiotracer (18)F-FRP170 in glioblastomas include regions retaining proliferative activity under hypoxia

OBJECTIVE: The aim was to evaluate the proliferative activity of high-uptake areas on positron emission tomography (PET) with the hypoxic cell radiotracer, 1-(2-[(18)F]fluoro-1-[hydroxymethyl]ethoxy)methyl-2-nitroimidazole (FRP170). METHODS: Thirteen patients with glioblastoma underwent FRP170 PET b...

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Detalles Bibliográficos
Autores principales: Beppu, Takaaki, Sasaki, Toshiaki, Terasaki, Kazunori, Saura, Hiroaki, Mtsuura, Hideki, Ogasawara, Kuniaki, Sasaki, Makoto, Ehara, Shigeru, Iwata, Ren, Takai, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661197/
https://www.ncbi.nlm.nih.gov/pubmed/25618012
http://dx.doi.org/10.1007/s12149-015-0951-0